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AMOT Monoclonal Antibody (OTI1A8), TrueMAB™, OriGene
SDP

Catalog No. 501676964
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100 μL
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50-167-6964 100 μL
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Catalog No. 50-167-6964 Supplier OriGene Supplier No. TA507127
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Description

Mouse Monoclonal Antibody

AMOT (Angiomotin) belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. AMOT plays a central role in tight junction maintece via the complex formed with ARHGAP17 - which acts by regulating the uptake of polarity proteins at tight junctions. AMOT is expressed predomitly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels.

Specifications

Antigen AMOT
Applications Western Blot
Classification Monoclonal
Clone OTI1A8
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene AMOT
Gene Accession No. Q4VCS5
Gene Alias angiomotin
Gene Symbols AMOT
Host Species Mouse
Immunogen Full length human recombit protein of human AMOT produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 154796
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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