AMOT Monoclonal Antibody (OTI1A8), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA507127

Catalog No. 50-167-6964

Description

AMOT (Angiomotin) belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. AMOT plays a central role in tight junction maintece via the complex formed with ARHGAP17 - which acts by regulating the uptake of polarity proteins at tight junctions. AMOT is expressed predomitly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels.

Specifications

• Antigen: AMOT
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q4VCS5
• Gene Symbols: AMOT
• Immunogen: Full length human recombit protein of human AMOT produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI1A8
• Conjugate: Unconjugated
• Gene: AMOT
• Gene Alias: angiomotin
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 154796
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid