Invitrogen™ AMOT Monoclonal Antibody (OTI3F9)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA526322

Catalog No. PIMA526322

Description

AMOT Monoclonal Antibody for Western Blot, IHC (P)

AMOT (Angiomotin) belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. AMOT plays a central role in tight junction maintenance via the complex formed with ARHGAP17 - which acts by regulating the uptake of polarity proteins at tight junctions. AMOT is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels.

Specifications

• Antigen: AMOT
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q4VCS5
• Gene Symbols: AMOT
• Immunogen: Full length human recombinant protein of AMOT produced in HEK293T cell.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI3F9
• Conjugate: Unconjugated
• Gene: AMOT
• Gene Alias: AMOT; Angiomotin; angiomotin p130 isoform; angiomotin p80 isoform; CAG-2; D0Kist1; KIAA1071; RGD1564027; si:dkey-13f9.6; Sii6; wu:fj21a07
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 154796
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid