AMOT Mouse anti-Human, Clone: OTI1A8, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF507127

Catalog No. 50-166-4644

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

AMOT (Angiomotin) belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. AMOT plays a central role in tight junction maintece via the complex formed with ARHGAP17 - which acts by regulating the uptake of polarity proteins at tight junctions. AMOT is expressed predomitly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels.

Specifications

• Antigen: AMOT
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: AMOT
• Gene Alias: angiomotin
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 154796
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Clone: OTI1A8
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q4VCS5
• Gene Symbols: AMOT
• Immunogen: Full length human recombit protein of human AMOT produced in HEK293T cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1