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Invitrogen™ AMOT Polyclonal Antibody
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Catalog No. PIPA564322
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100 μL
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PIPA564322 100 μL
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Catalog No. PIPA564322 Supplier Invitrogen™ Supplier No. PA564322
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LSERLMQMSL ATSGVKAHPP VTSAPLSPPQ PNDLYKNPTS SSEFYKAQGP LPNQHSLKGM EHRG Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.

AMOT (Angiomotin) belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. AMOT plays a central role in tight junction maintenance via the complex formed with ARHGAP17 - which acts by regulating the uptake of polarity proteins at tight junctions. AMOT is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels.
TRUSTED_SUSTAINABILITY

Specifications

Antigen AMOT
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene AMOT
Gene Accession No. Q4VCS5
Gene Alias AMOT; Angiomotin; angiomotin p130 isoform; angiomotin p80 isoform; CAG-2; D0Kist1; KIAA1071; RGD1564027; si:dkey-13f9.6; Sii6; wu:fj21a07
Gene Symbols AMOT
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human AMOT. Recombinant protein control fragment (Product #RP-103986).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 154796
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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