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Invitrogen™ AMOT Polyclonal Antibody
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Catalog No. PIPA5103603
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100 μL
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Catalog No. Quantity
PIPA5103603 100 μL
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Catalog No. PIPA5103603 Supplier Invitrogen™ Supplier No. PA5103603
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total AMOT.

AMOT (Angiomotin) belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. AMOT plays a central role in tight junction maintenance via the complex formed with ARHGAP17 - which acts by regulating the uptake of polarity proteins at tight junctions. AMOT is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels.
TRUSTED_SUSTAINABILITY

Specifications

Antigen AMOT
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene AMOT
Gene Accession No. Q4VCS5, Q8VHG2
Gene Alias AMOT; Angiomotin; angiomotin p130 isoform; angiomotin p80 isoform; CAG-2; D0Kist1; KIAA1071; RGD1564027; si:dkey-13f9.6; Sii6; wu:fj21a07
Gene Symbols AMOT
Host Species Rabbit
Immunogen A synthesized peptide derived from human AMOT(Accession Q4VCS5), corresponding to amino acid residues Y836-P886.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 154796, 27494
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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