AMOT Mouse anti-Human, Clone: OTI3F9, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA526322
DescriptionAMOT (Angiomotin) belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. AMOT plays a central role in tight junction maintece via the complex formed with ARHGAP17 - which acts by regulating the uptake of polarity proteins at tight junctions. AMOT is expressed predomitly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|angiomotin p130 isoform, angiomotin p80 isoform|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of AMOT produced in HEK293T cell|
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