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AMOT Mouse anti-Human, Clone: OTI3F9, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA526322

Catalog No. PIMA526322


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Description

Description

AMOT (Angiomotin) belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. AMOT plays a central role in tight junction maintece via the complex formed with ARHGAP17 - which acts by regulating the uptake of polarity proteins at tight junctions. AMOT is expressed predomitly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels.
Specifications

Specifications

AMOT
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q4VCS5
angiomotin p130 isoform, angiomotin p80 isoform
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
154796
Immunohistochemistry (Paraffin), Western Blot
OTI3F9
Unconjugated
AMOT
Liquid
AMOT
Full length human recombit protein of AMOT produced in HEK293T cell
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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