Invitrogen™ AMOTL2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA598594

Catalog No. PIPA598594

Description

AMOTL2 Polyclonal Antibody for Western Blot, ELISA

Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. Participates in angiogenesis. May play a role in the polarity, proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPK activation through SRC.

Specifications

• Antigen: AMOTL2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: AMOTL2
• Gene Alias: AMOTL2; angiomotin like 2; angiomotin-like 2; angiomotin-like protein 2; AW549739; C79691; KIAA0989; LCCP; Leman coiled-coil protein; MASCOT; mKIAA0989
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51421
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.19 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: Q9Y2J4
• Gene Symbols: AMOTL2
• Immunogen: Peptide sequence from Human Angiomotin-like protein 2 protein (718-737AA).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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