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Description
This gene encodes a member of the AMP deaminase gene family. The encoded protein is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. This gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. Mutations in this gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq]
Specifications
Specifications
| Antigen | AMPD3 |
| Applications | Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (PFA fixed) |
| Classification | Monoclonal |
| Clone | AMPD3/901 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against full length recombinant human AMPD3. |
| Dilution | Flow Cytometry (1-2 ug/106 cells in 0.1 mL) Immunocytochemistry (1-2 ug/mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2-4 ug/mL) The optimal working dilution should be det |
| Formulation | In 10mM PBS. |
| Gene Symbols | AMPD3 |
| Host Species | Mouse |
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