Thermo Scientific Chemicals Ampicillin, Ready-to-Use aqueous soln., 100mg/mL, 0.2 micron filtered

Catalog No.	Quantity
AAJ66972AB	10 mL
AAJ66972AC	25 mL

Catalog No. AAJ66972AB Supplier Thermo Scientific Chemicals Supplier No. J66972AB

Description

Ampicillin, CAS # 69-53-4, is structurally related to penicillin and is considered to be a semi-synthetic antibiotic with antibacterial activity. | CAS: 69-53-4 | C16H19N3O4S | 349.405 g/mol

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Ampicillin is a broad-spectrum, semi-synthetic, β-lactam penicillin with bactericidal activity. It acts against several gram-positive and -negative infections
• This compound binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. This inactivation interferes with the cross-linkage of peptidoglycan chains essential for bacterial cell wall strength and rigidity. Consequently, there is an interruption in the bacterial cell wall synthesis which results in the weakening of the bacterial cell wall causing cell lysis

Application

• In laboratory experiments, it is commonly used as a selector reagent for transformed cells expressing β-lactamase. The ampicillin-resistant gene (ampR) catalyzes the hydrolysis of the β-lactam ring of ampicillin and naturally detoxifies the drug
• Ampicillin is commonly used as a selection marker for E. coli and other bacteria during plasmid DNA isolation, protein expression, and gene cloning

Specifications

Chemical Identifiers

• CAS: 69-53-4
• Molecular Formula: C16H19N3O4S
• Molecular Weight (g/mol): 349.405
• InChI Key: AVKUERGKIZMTKX-NJBDSQKTSA-N
• PubChem CID: 6249
• ChEBI: CHEBI:28971
• IUPAC Name: (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• SMILES: CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)O)C

• Type: Ampicillin
• Physical Form: Liquid
• Odor: Odorless
• Color: Yellow
• Quantity: 10 mL
• Sensitivity: Light sensitive
• Chemical Name or Material: Ampicillin, eady-to-Use aqueous soln., 100mg/mL, 0.2 micron filtered

Safety and Handling

Hazard Category	H317-H334
Hazard Statement	GHS H Statement H334-H317 May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction.
Precautionary Statement	P261-P272-P280g-P285-P302+P352-P304+P341-P333+P313-P342+P311-P363-P501c
EINECSNumber	200-708-1
RTECSNumber	XH8400000
TSCA	No
storageNote1	-30° to -10°C
Recommended Storage	Store at -20°C

SDS

RUO – Research Use Only