Invitrogen™ AMPK alpha-1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120472

Catalog No. PIPA5120472

Description

Positive test controls include: PC-12, Rat liver. The target is usually found in the following locations: Cytoplasm, Nucleus. Immunogen sequence: MAEVCRAIKQ LDYEWKVVNP YYLRVRRKNP VTSTYSKMSL QLYQVDSRTY LLDFRSIDDE ITEAKSGTAT PQRSGSVSNY RSCQRSDSDA EAQGKSSEVS.

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.

Specifications

• Antigen: AMPK alpha-1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Prkaa1
• Gene Alias: 5'-AMP-activated protein kinase alpha-1 catalytic subunit; 5'-AMP-activated protein kinase catalytic subunit alpha-1; 5'-AMP-activated protein kinase, catalytic alpha-1 chain; 63 kDa subunit; AAPK2; ACACA kinase; Acetyl-CoA carboxylase kinase; activated protein kinase; AI194361; AI450832; AL024255; AMP -activate kinase alpha 1 subunit; AMP activated protein kinase; AMP-activated protein kinase, alpha 1 catalytic subunit; AMP-activated protein kinase, catalytic, alpha-1; AMPK; AMPK 63 kDa subunit; AMPK alpha 1; AMPK alpha-1 chain; AMPK subunit alpha-1; AMPK subunit pAMPK; AMPK1; AMPK2; AMPKa1; AMPKalpha1; AMPK-alpha-2 chain; C130083N04Rik; HMGCR kinase; hydroxymethylglutaryl-CoA reductase kinase; MGC33776; MGC57364; pAMPK; PRKAA; Prkaa1; PRKAA2; protein kinase; protein kinase AMP-activated catalytic subunit alpha 1; protein kinase, AMP-activated, alpha 1 catalytic subunit; tau-protein kinase PRKAA1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 105787, 5562, 65248
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 3.57 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P54645, Q13131, Q5EG47
• Gene Symbols: Prkaa1
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 421-520 of human AMPKalpha1 (NP_0062425).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG