Invitrogen™ AMPK gamma-3 Monoclonal Antibody (1C5D10)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA531869

Catalog No. PIMA531869

Description

MA5-31869 has been tested in indirect ELISA.

The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle.

Specifications

• Antigen: AMPK gamma-3
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: Q9UGI9
• Gene Symbols: PRKAG3
• Immunogen: Purified recombinant fragment of human PRKAG3 (AA: 9-151) expressed in E. coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Western Blot
• Clone: 1C5D10
• Conjugate: Unconjugated
• Gene: PRKAG3
• Gene Alias: 5'-AMP-activated protein kinase subunit gamma-3; 5'-AMP-activated protein kinase, gamma-3 subunit; Amkg3; AMP-activated protein kinase gamma 3 subunit; AMP-activated protein kinase gamma subunit; ampk gamma; AMPK gamma3; AMPK gamma-3 chain; AMPK subunit gamma-3; Ampkg3; AMPKg3L; AMPKg3S; OTTHUMP00000206393; PRKAG3; protein kinase AMP-activated non-catalytic subunit gamma 3; protein kinase, AMP-activated, gamma 3 non-catalytic subunit; protein kinase, AMP-activated, gamma 3 non-catatlytic subunit
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 53632
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid