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Invitrogen™ AMPK gamma-3 Monoclonal Antibody (2C7A7)
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Catalog No. PIMA531868
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100 μL
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PIMA531868 100 μL
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Catalog No. PIMA531868 Supplier Invitrogen™ Supplier No. MA531868
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Description

Mouse Monoclonal Antibody

MA5-31868 has been tested in indirect ELISA.

The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle.
TRUSTED_SUSTAINABILITY

Specifications

Antigen AMPK gamma-3
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 2C7A7
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene PRKAG3
Gene Accession No. Q9UGI9
Gene Alias 5'-AMP-activated protein kinase subunit gamma-3; 5'-AMP-activated protein kinase, gamma-3 subunit; Amkg3; AMP-activated protein kinase gamma 3 subunit; AMP-activated protein kinase gamma subunit; ampk gamma; AMPK gamma3; AMPK gamma-3 chain; AMPK subunit gamma-3; Ampkg3; AMPKg3L; AMPKg3S; OTTHUMP00000206393; PRKAG3; protein kinase AMP-activated non-catalytic subunit gamma 3; protein kinase, AMP-activated, gamma 3 non-catalytic subunit; protein kinase, AMP-activated, gamma 3 non-catatlytic subunit
Gene Symbols PRKAG3
Host Species Mouse
Immunogen Purified recombinant fragment of human PRKAG3 (AA: 9-151) expressed in E. coli.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 53632
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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