AMPK gamma 3/PRKAG3 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-5799	100 μL

Catalog No. 50-198-5799 Supplier Bioss Supplier No. BS3968R

Description

Rabbit Polyclonal Antibody

The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle.

Specifications

• Antigen: AMPK gamma 3/PRKAG3
• Applications: ELISA, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: PRKAG3
• Gene Accession No.: Q9UGI9
• Gene Alias: 5′-AMP-activated protein kinase subunit gamma-3; 5′-AMP-activated protein kinase, gamma-3 subunit; AMPK gamma3; AMPK gamma-3 chain; AMPK subunit gamma-3; AMPKG3; OTTHUMP00000206393; PRKAG3; protein kinase AMP-activated non-catalytic subunit gamma 3; protein kinase, AMP-activated, gamma 3 non-catalytic subunit
• Gene Symbols: PRKAG3
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human AMPK gamma 3.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 53632
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG