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Invitrogen™ Amylin Monoclonal Antibody (C2), Invitrogen™
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Catalog No. PIMA543963
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100 μL
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PIMA543963 100 μL
PIMA543964 20 μL
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Catalog No. PIMA543963 Supplier Invitrogen™ Supplier No. MA543963
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Description

Mouse Monoclonal Antibody

The target peptide sequence is KCNTATCATQRLANFLV.

Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the association of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Amylin
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone C2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
Gene IAPP
Gene Accession No. P10997
Gene Alias Amylin; amylin peptide; DAP; Diabetes-associated peptide; IAP; Iapp; Insulinoma amyloid peptide; islet amyloid polypeptide; Islet amyloid polypeptide (diabetes-associated peptide; amylin); Rabbit Anti-Amylin
Gene Symbols IAPP
Host Species Mouse
Immunogen Recombinant Amylin (Lys34-Val50).
Purification Method Protein A/G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3375
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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