Invitrogen™ Amylin Monoclonal Antibody (C2), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA543964

Catalog No. PIMA543964

Description

The target peptide sequence is KCNTATCATQRLANFLV.

Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the association of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.

Specifications

• Antigen: Amylin
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300
• Gene Accession No.: P10997
• Gene Symbols: IAPP
• Immunogen: Recombinant Amylin (Lys34-Val50).
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: Immunohistochemistry (Paraffin)
• Clone: C2
• Conjugate: Unconjugated
• Gene: IAPP
• Gene Alias: Amylin; amylin peptide; DAP; Diabetes-associated peptide; IAP; Iapp; Insulinoma amyloid peptide; islet amyloid polypeptide; Islet amyloid polypeptide (diabetes-associated peptide; amylin); Rabbit Anti-Amylin
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 3375
• Content And Storage: -20°C
• Form: Liquid