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Invitrogen™ Amylin Polyclonal Antibody
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Catalog No. PIPA584142
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100 μL
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PIPA584142 100 μL
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Catalog No. PIPA584142 Supplier Invitrogen™ Supplier No. PA584142
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LVHSSNNFGA ILSSTNVGSN TYGKRNAVEV LKREPLNYLP Highest antigen sequence indentity to the following orthologs: Rat - 63%, Mouse - 63%.

Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the association of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.
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Specifications

Antigen Amylin
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene IAPP
Gene Accession No. P10997
Gene Alias Amylin; amylin peptide; DAP; Diabetes-associated peptide; IAP; Iapp; Insulinoma amyloid peptide; islet amyloid polypeptide; Islet amyloid polypeptide (diabetes-associated peptide; amylin); Rabbit Anti-Amylin
Gene Symbols IAPP
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human IAPP. Recombinant protein control fragment (Product #RP-101656).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3375
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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