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Invitrogen™ Amylin Polyclonal Antibody
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Catalog No. PIPA5102889
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100 μL
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PIPA5102889 100 μL
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Catalog No. PIPA5102889 Supplier Invitrogen™ Supplier No. PA5102889
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Amylin.

Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the association of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.
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Specifications

Antigen Amylin
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene IAPP
Gene Accession No. P10997, P12968, P12969
Gene Alias Amylin; amylin peptide; DAP; Diabetes-associated peptide; IAP; Iapp; Insulinoma amyloid peptide; islet amyloid polypeptide; Islet amyloid polypeptide (diabetes-associated peptide; amylin); Rabbit Anti-Amylin
Gene Symbols IAPP
Host Species Rabbit
Immunogen A synthesized peptide derived from human IAPP(Accession P10997), corresponding to amino acid residues F9-I59.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15874, 24476, 3375
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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