Invitrogen™ AMZ2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA565722

Catalog No. PIPA565722

Description

Immunogen sequence: PICLHKLQCAV GFSIVERYKA LVRWIDDESS DTPGATPEHS HEDNGNLPKP VEAFKEWKEW II Highest antigen sequence identity to the following orthologs - mouse 67%, rat 70%.

AMZ2 (archaelysin family metallopeptidase 2), also known as archaemetzincin-2 or archeobacterial metalloproteinase-like protein 2, is a 360 amino acid protein belonging to the peptidase M54 family. Encoded by a gene that maps to human chromosome 17q24.2, AMZ2 is predominantly expressed in heart and testis. AMZ2 is also expressed in kidney, liver, pancreas, lung, brain and placenta, and in fetal tissues such as kidney, liver, lung and brain. AMZ2 participates in metal ion binding and functions as a zinc metalloprotease. AMZ2 is inhibited by both general metalloprotease inhibitors o-phenanthroline and batimastat. Exhibiting aminopeptidase activity, AMZ2 acts against Angiotensin in vitro, but does not hydrolyze either Neurogranin or Angiotensin.

Specifications

• Antigen: AMZ2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: AMZ2
• Gene Alias: AA408420; Amz2; archaelysin family metallopeptidase 2; archaemetzincin-2; archaemetzincins-2; archeobacterial metalloproteinase-like 2; archeobacterial metalloproteinase-like protein 2; BM-014; ESTM12; RGD1304846; X83328
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51321
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q86W34
• Gene Symbols: AMZ2
• Immunogen: Recombinant Human AMZ2. Recombinant protein control fragment (Product #RP-106395).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov