Invitrogen™ Angiogenin Monoclonal Antibody (14017.7)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA120177

Catalog No. MA120177

Description

Recommended positive controls: mouse liver. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Angiogenin (ANG or ANG I) is important for the process of neovascularization and formation of new blood vessels. ANG is similar to pancreatic ribonuclease A and functions as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. It interacts with endothelial cell-surface actin and may cause changes in the cell cytoskeleton. ANG is thought to be involved in the development of solid tumors and its antagonists are capable of inhibiting tumor growth. Defects in ANG are the cause of susceptibility to amyotrophic lateral sclerosis type 9 (ALS9). Angiogenin is a genetic link between ALS and PD.

Specifications

• Antigen: Angiogenin
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: P03950
• Gene Symbols: ANG
• Immunogen: Recombinant, full length, human angiogenin protein.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Immunohistochemistry, Western Blot
• Clone: 14017.7
• Conjugate: Unconjugated
• Gene: ANG
• Gene Alias: AI385586; ALS9; ANG; Ang1; Angiogenin; angiogenin ribonuclease 1; angiogenin, ribonuclease A family, member 1; angiogenin, ribonuclease, RNase A family, 5; angiogenin-1; epididymis luminal protein 168; HEL168; MGC22466; MGC71966; RAA1; Ribonuclease 5; ribonuclease A A1; ribonuclease A family member 5; RNase 5; RNASE4; RNASE5; Rnase5a
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 283
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid