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Invitrogen™ Angiogenin Monoclonal Antibody (14017)
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Catalog No. MA120177
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100 μg
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Catalog No. Quantity
MA120177 100 μg
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Catalog No. MA120177 Supplier Invitrogen™ Supplier No. MA120177
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Description

Mouse Monoclonal Antibody

Recommended positive controls: mouse liver. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Angiogenin (ANG or ANG I) is important for the process of neovascularization and formation of new blood vessels. ANG is similar to pancreatic ribonuclease A and functions as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. It interacts with endothelial cell-surface actin and may cause changes in the cell cytoskeleton. ANG is thought to be involved in the development of solid tumors and its antagonists are capable of inhibiting tumor growth. Defects in ANG are the cause of susceptibility to amyotrophic lateral sclerosis type 9 (ALS9). Angiogenin is a genetic link between ALS and PD.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Angiogenin
Applications ELISA, Immunohistochemistry, Western Blot
Classification Monoclonal
Clone 14017
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and no preservative
Gene ANG
Gene Accession No. P03950
Gene Alias AI385586; ALS9; ANG; Ang1; Angiogenin; angiogenin ribonuclease 1; angiogenin, ribonuclease A family, member 1; angiogenin, ribonuclease, RNase A family, 5; angiogenin-1; epididymis luminal protein 168; HEL168; MGC22466; MGC71966; RAA1; Ribonuclease 5; ribonuclease A A1; ribonuclease A family member 5; RNase 5; RNASE4; RNASE5; Rnase5a
Gene Symbols ANG
Host Species Mouse
Immunogen Purified recombinant human angiogenin expressed in E. coli.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 283
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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