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Invitrogen™ Angiogenin Polyclonal Antibody
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Catalog No. PIPA534422
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100 μg
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Catalog No. Quantity
PIPA534422 100 μg
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Catalog No. PIPA534422 Supplier Invitrogen™ Supplier No. PA534422
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Description

Rabbit Polyclonal Antibody

A suggested positive control is rat liver tissue lysate. PA5-34422 can be used with blocking peptide PEP-1464.

Angiogenin (ANG or ANG I) is important for the process of neovascularization and formation of new blood vessels. ANG is similar to pancreatic ribonuclease A and functions as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. It interacts with endothelial cell-surface actin and may cause changes in the cell cytoskeleton. ANG is thought to be involved in the development of solid tumors and its antagonists are capable of inhibiting tumor growth. Defects in ANG are the cause of susceptibility to amyotrophic lateral sclerosis type 9 (ALS9). Angiogenin is a genetic link between ALS and PD.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Angiogenin
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene ANG
Gene Accession No. P03950, P21570
Gene Alias AI385586; ALS9; ANG; Ang1; Angiogenin; angiogenin ribonuclease 1; angiogenin, ribonuclease A family, member 1; angiogenin, ribonuclease, RNase A family, 5; angiogenin-1; epididymis luminal protein 168; HEL168; MGC22466; MGC71966; RAA1; Ribonuclease 5; ribonuclease A A1; ribonuclease A family member 5; RNase 5; RNASE4; RNASE5; Rnase5a
Gene Symbols ANG
Host Species Rabbit
Immunogen A 15 amino acid synthetic peptide near the center of human ANG.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11727, 283, 305843
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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