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Invitrogen™ Angiogenin Polyclonal Antibody
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Catalog No. PIPA578773
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100 μg
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PIPA578773 100 μg
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Catalog No. PIPA578773 Supplier Invitrogen™ Supplier No. PA578773
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Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human hepatocellular carcinoma tumor tissue (HCCT). IHC: human hepatocellular carcinoma tissue, human lung cancer tissue. ICC/IF: U2OS cell. Flow: HepG2 cell.

Angiogenin (ANG or ANG I) is important for the process of neovascularization and formation of new blood vessels. ANG is similar to pancreatic ribonuclease A and functions as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. It interacts with endothelial cell-surface actin and may cause changes in the cell cytoskeleton. ANG is thought to be involved in the development of solid tumors and its antagonists are capable of inhibiting tumor growth. Defects in ANG are the cause of susceptibility to amyotrophic lateral sclerosis type 9 (ALS9). Angiogenin is a genetic link between ALS and PD.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Angiogenin
Applications ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and no preservative
Gene ANG
Gene Accession No. P03950
Gene Alias AI385586; ALS9; ANG; Ang1; Angiogenin; angiogenin ribonuclease 1; angiogenin, ribonuclease A family, member 1; angiogenin, ribonuclease, RNase A family, 5; angiogenin-1; epididymis luminal protein 168; HEL168; MGC22466; MGC71966; RAA1; Ribonuclease 5; ribonuclease A A1; ribonuclease A family member 5; RNase 5; RNASE4; RNASE5; Rnase5a
Gene Symbols ANG
Host Species Rabbit
Immunogen E. coli-derived human Angiogenin/ANG recombinant protein (Position: Q25-P147).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 283
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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