Invitrogen™ Angiopoietin 1 Monoclonal Antibody (171718)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA523884

Catalog No. PIMA523884

Description

In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) Angiopoietin-2, recombinant mouse Angiopoietin-like 3, rhAngiopoietin-4, or rhAngiopoietin-like 7 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart.

Specifications

• Antigen: Angiopoietin 1
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: Q15389
• Gene Symbols: Angpt1
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Angiopoietin-1 Ser20-Phe498.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: 171718
• Conjugate: Unconjugated
• Gene: Angpt1
• Gene Alias: 1110046O21Rik; 2810039D03Rik; AGP1; Agpt; Agpt1; ANG1; ang-1; ANG3; ANG-3; angioarrestin; angiopoietin 1; angiopoietin 3; angiopoietin like 1; angiopoietin Y1; angiopoietin-1; Angiopoietin-3; angiopoietin-like 1; angiopoietin-like protein 1; Angiopoietin-related protein 1; Angpt1; ANGPT3; Angptl1; AngY; ARP1; dJ595C2.2; dJ595C2.2 (angiopoietin Y1); endothelial growth factor; KIAA0003; PSEC0154; tie2 receptor ligand; UNQ162; UNQ162/PRO188
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 284
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized