Angiopoietin 1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA596841

Catalog No. PIPA596841

Description

Immunogen sequence: REEEKPFRDC ADVYQAGFNK SGIYTIYINN MPEPKKVFCN MDVNGGGWTV IQHREDGSLD FQRGWKEYKM GFGNPSGEYW LGNEFIFAIT SQRQYMLRIE LMDWEGNRAY SQYDRFHIGN EKQNYRLYLK GHTGTAGKQS SLILHGADFS TKDADNDNCM CKCALMLTGG WWFDACGPSN LNGMFYTAGQ NHGKLNGIKW HYFKGPSYSL RSTTMMIRPL DF Positive Samples: A549, mouse lung

Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart.

Specifications

• Antigen: Angiopoietin 1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Angpt1
• Gene Alias: 1110046O21Rik, 2810039D03Rik, AGP1, Agpt, Agpt1, ANG1, ang-1, ANG3, ANG-3, angioarrestin, angiopoietin 1, angiopoietin 3, angiopoietin like 1, angiopoietin Y1, angiopoietin-1, Angiopoietin-3, angiopoietin-like 1, angiopoietin-like protein 1, Angiopoietin-related protein 1, Angpt1, ANGPT3, Angptl1, AngY, ARP1, dJ595C2.2, dJ595C2.2 (angiopoietin Y1), endothelial growth factor, KIAA0003, PSEC0154, tie2 receptor ligand, UNQ162, UNQ162/PRO188
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11600, 284, 89807
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.62 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
• Gene Accession No.: O08538, O35460, Q15389
• Gene Symbols: Angpt1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 277-498 of human ANGPT1 (NP_001137.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov