Invitrogen™ Angiotensinogen Recombinant Rabbit Monoclonal Antibody (001)

Catalog No.	Quantity
PIMA536045	100 μL

Catalog No. PIMA536045 Supplier Invitrogen™ Supplier No. MA536045

Description

Rabbit Recombinant Monoclonal Antibody

Angiotensinogen Recombinant Monoclonal Antibody for Western Blot

The protein encoded by AGT, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

Specifications

• Antigen: Angiotensinogen
• Applications: Western Blot
• Classification: Recombinant Monoclonal
• Clone: 001
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with no preservative
• Gene: AGT
• Gene Accession No.: P11859
• Gene Alias: AGT; AI265500; alpha-1 antiproteinase, antitrypsin; Ang; Ang I; Ang II; Ang III; Ang IV; AngI; AngII; Angiotensin 1-10; Angiotensin 1-4; Angiotensin 1-5; Angiotensin 1-7; Angiotensin 1-8; Angiotensin 1-9; Angiotensin 2-8; Angiotensin 3-8; Angiotensin I; angiotensin II; Angiotensin III; Angiotensin IV; angiotensin ll; Angiotensin-1; Angiotensin-2; Angiotensin-3; Angiotensin-4; Angiotensinogen; angiotensinogen (PAT); angiotensinogen (serpin peptidase inhibitor, clade A, member 8); ANHU; ANRT; Aogen; Des-Asp[1]-angiotensin II; PAT; pre-angiotensinogen; serine (or cysteine) proteinase inhibitor; serpin A8; serpin peptidase inhibitor, clade A, member 8; Serpina8
• Gene Symbols: AGT
• Host Species: Rabbit
• Immunogen: Recombinant Mouse Angiotensinogen/AGT Protein.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 11606
• Target Species: Mouse
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG