Thermo Scientific Chemicals Anisomycin, 10 mg/ml in DMSO, sterile-filtered

Catalog No.	Quantity
AAJ67498XF	1 mL

Catalog No. AAJ67498XF Supplier Thermo Scientific Chemicals Supplier No. J67498XF

Description

CAS: 22862-76-6 | C14H19NO4 | 265.31 g/mol

It is applied as an antiparasitic agent and antineoplastic agent. It acts as a protein synthesis inhibitor (blocks translation), potent activator of stress-activated protein kinases (JNK/SAPK) and p38 MAP kinase. It also scts as a potent signaling agonist to selectively elicit homologous desensitization of immediate early gene induction (c-fos, fosB, c-jun, junB and junD). Activates mitogen-activated protein (MAP) kinases (JNK/SAPK and p38/RK).

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is applied as an antiparasitic agent and antineoplastic agent. It acts as a protein synthesis inhibitor (blocks translation), potent activator of stress-activated protein kinases (JNK/SAPK) and p38 MAP kinase. It also scts as a p

Specifications

Chemical Identifiers

• CAS: 22862-76-6
• Molecular Formula: C14H19NO4
• Molecular Weight (g/mol): 265.31
• MDL Number: MFCD00077650
• InChI Key: YKJYKKNCCRKFSL-BFHYXJOUSA-N
• Synonym: Flagecidin
• PubChem CID: 253602
• ChEBI: CHEBI:338412
• IUPAC Name: (2S,3R,4R)-4-hydroxy-2-[(4-methoxyphenyl)methyl]pyrrolidin-3-yl acetate
• SMILES: COC1=CC=C(C[C@@H]2NC[C@@H](O)[C@@H]2OC(C)=O)C=C1

• Type: Anisomycin
• Physical Form: Liquid
• Quantity: 1 mL
• Solubility Information: Fully miscible in water. Soluble to 50 mM in ethanol and to 100 mM in DMSO. Soluble in methanol (20mg/ml clear,faint yellow solution).Slightly soluble in alcohols,esters,ketones,chloroform,benzene,toluene,hexane,and ethyl acetate (10mg/ml clear,colorless solution),DMF (20mg/ml),and PBS pH 7.2 (0.5mg/ml).
• Chemical Name or Material: Anisomycin, 10mg/mL in DMSO, sterile-filtered

Safety and Handling

Hazard Category	H227
Hazard Statement	GHS H Statement H227 Combustible liquid.
Precautionary Statement	P210-P280-P370+P378q-P501c
EINECSNumber	245-269-7
RTECSNumber	BZ9800000
TSCA	No
storageNote1	-30° to -10°C
Recommended Storage	Store at -20°C

SDS

RUO – Research Use Only