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Invitrogen™ ANKLE2 Polyclonal Antibody
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Catalog No. PIPA551973
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100 μL
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PIPA551973 100 μL
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Catalog No. PIPA551973 Supplier Invitrogen™ Supplier No. PA551973
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SETVNKERAN SYKNPRTQDL TAKLRKAVEK GEEDTFSDLI WSNPRYLIGS GDNPTIVQEG CRYNVMHVAA KENQASICQL TLDVLENPDF MRLMYPDDDE AMLQKRIRYV VDLYLNTPDK MGYDTPLHFA CKFGNADVVN VLSSH Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 90%.

This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ANKLE2
Applications Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ANKLE2
Gene Accession No. Q86XL3
Gene Alias 1110001J12Rik; Ab2-034; AI661024; Ankle2; ankyrin repeat and LEM domain containing 2; ankyrin repeat and LEM domain-containing protein 2; D5Ertd585e; Kiaa0692; LEM domain containing 7; LEM domain-containing protein 4; LEM4; LEMD7; liver regeneration-related protein LRRG057; MCPH16; RGD1310191
Gene Symbols ANKLE2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ANKLE2. Recombinant protein control fragment (Product #RP-102178).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23141
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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