Invitrogen™ ANKRD13A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA558812

Catalog No. PIPA558812

Description

Immunogen sequence: FGNVNGCSTA EESVSQNVEG TQADSASHIT NFEVDQSVFE IPESYYVQDN GRNVHLQDED YEIMQFAI Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 86%.

ANKRD13A, also named as ANKRD13, a 590 amino acid protein, which contains two ANK repeats and four UIM (ubiquitin-interacting motif) repeats. ANKRD13A localizes in the cell membrane. ANKRD13A as ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin, not bind 'Lys-48'-linked ubiquitin. ANKRD13A positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

Specifications

• Antigen: ANKRD13A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ANKRD13A
• Gene Alias: 1100001D10Rik; Ankrd13; ANKRD13A; ankyrin repeat domain 13; ankyrin repeat domain 13A; ankyrin repeat domain-containing protein 13A; AU046136; NY-REN-25; NY-REN-25 antigen; Protein KE03
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 88455
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8IZ07
• Gene Symbols: ANKRD13A
• Immunogen: Recombinant protein corresponding to Human AN13A. Recombinant protein control fragment (Product #RP-97637).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG