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ANKRD20A3 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501989313
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Catalog No. Quantity
50-198-9313 100 μL
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Catalog No. 50-198-9313 Supplier Bioss Supplier No. BS9747R
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Description

Rabbit Polyclonal Antibody

Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD20A (ankyrin repeat domain-containing protein 20A) is an 823 amino acid protein that contains five ANK repeats. The gene encoding ANKRD20A maps to chromosome 9, which consists of about 145 million bases and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and familial dysautonomia are associated with chromosome 9. Also, chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.

Specifications

Antigen ANKRD20A3
Applications Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene ANKRD20A3
Gene Accession No. Q5VUR7
Gene Alias ANKRD20A3; ankyrin repeat domain 20 family member A3; ankyrin repeat domain 20 family, member A3; ankyrin repeat domain 20A-related; Ankyrin repeat domain-containing protein 20A3
Gene Symbols ANKRD20A3
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human ANKRD20A3.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 441425
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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