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Invitrogen™ ANKRD32 Polyclonal Antibody
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Catalog No. PIPA559301
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100 μL
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PIPA559301 100 μL
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Catalog No. PIPA559301 Supplier Invitrogen™ Supplier No. PA559301
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: EYAKESKAMA IKTDVDVVEI KNTLRKHIYR AQAVRYNCIR IDKQPVYNVE VKNAEFPRGV LNLIESLIEG HFFKEAIEEL STLQAHYIPP VC Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 74%.

Plays a role in the DNA damage response (DDR) pathway by regulating postreplication repair of UV-damaged DNA and genomic stability maintenance (PubMed:25931565). The SLF1-SLF2 complex acts to link RAD18 with the SMC5-SMC6 complex at replication-coupled interstrand cross-links (ICL) and DNA double-strand breaks (DSBs) sites on chromatin during DNA repair in response to stalled replication forks (PubMed:25931565). Promotes the recruitment of SLF2 and the SMC5-SMC6 complex to DNA lesions (PubMed:25931565).
TRUSTED_SUSTAINABILITY

Specifications

Antigen ANKRD32
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SLF1
Gene Accession No. Q9BQI6
Gene Alias 2700017A04Rik; ANKRD32; ankyrin repeat domain 32; ankyrin repeat domain-containing protein 32; AW545819; BRCT domain containing 1; BRCT domain-containing protein 1; BRCTD1; Brctx; C730024G01Rik; Protein BRCTx; SLF1; Smc5/6 localization factor 1; SMC5-SMC6 complex localization factor 1; SMC5-SMC6 complex localization factor protein 1
Gene Symbols SLF1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ANKRD32. Recombinant protein control fragment (Product #RP-96854).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84250
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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