Invitrogen™ ANKRD32 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA565851

Catalog No. PIPA565851

Description

Immunogen sequence: SWLQMFVAEAV FKKLCLQSSG SVSSEPLSLQ KMVYSYLPAL GKTGVLGSGK IQVSKKIGQR PCFDSQRTLL MLNGTKQKQV EGLP Highest antigen sequence identity to the following orthologs - mouse 67%, rat 67%.

Plays a role in the DNA damage response (DDR) pathway by regulating postreplication repair of UV-damaged DNA and genomic stability maintenance (PubMed:25931565). The SLF1-SLF2 complex acts to link RAD18 with the SMC5-SMC6 complex at replication-coupled interstrand cross-links (ICL) and DNA double-strand breaks (DSBs) sites on chromatin during DNA repair in response to stalled replication forks (PubMed:25931565). Promotes the recruitment of SLF2 and the SMC5-SMC6 complex to DNA lesions (PubMed:25931565).

Specifications

• Antigen: ANKRD32
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLF1
• Gene Alias: 2700017A04Rik; ANKRD32; ankyrin repeat domain 32; ankyrin repeat domain-containing protein 32; AW545819; BRCT domain containing 1; BRCT domain-containing protein 1; BRCTD1; Brctx; C730024G01Rik; Protein BRCTx; SLF1; Smc5/6 localization factor 1; SMC5-SMC6 complex localization factor 1; SMC5-SMC6 complex localization factor protein 1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84250
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9BQI6
• Gene Symbols: SLF1
• Immunogen: Recombinant Human ANKRD32. Recombinant protein control fragment (Product #RP-106517).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov