Invitrogen™ ANKS1B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5121141

Catalog No. PIPA5121141

Description

Positive test controls include: A-549, Mouse liver. The target is usually found in the following locations: Cajal body, Cell junction, Cell projection, Cytoplasm, Nucleus, dendritic spine, postsynaptic cell membrane, postsynaptic density, synapse. Immunogen sequence: GFPFSAIHQV HNTGDWGEPS ITLRPPNEAT ASTPVQYWQH HPEKLIFQSC DYKAFYLGSM LIKELRGTES TQDACAKMRA NCQKSTEQMK KVPTIILSVS YKGVKFIDAT NKNIIAEHEI RNISCAAQDP EDLSTFAYIT KDLKSNHHYC HVFTAFDVNL AYEIILTLGQ AFEVAYQLAL QARKGGHSST LPESFENKPS KPIPKPRVSI RKSVQIDPSE QKTLANLPWI VEPGQEAKRG INTKYETTIF.

This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization) have been described for this gene.

Specifications

• Antigen: ANKS1B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ANKS1B
• Gene Alias: AIDA; AIDA-1; AIDA-1b; amyloid-beta precursor protein intracellular domain associated protein 1; amyloid-beta protein intracellular domain-associated protein 1; ANKS1B; ANKS2; ankyrin repeat and sterile alpha motif domain containing 1B; ankyrin repeat and sterile alpha motif domain-containing protein 1B; C030032C09Rik; cajalin 2; cajalin-2; E2A-PBX1-associated protein; E530015N03Rik; EB1; EB-1; ENSMUSG00000078431; Gm10937; Gm1555; MGC26087; RGD1565556
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 314721, 56899, 77531
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.45 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P0C6S7, Q7Z6G8, Q8BIZ1
• Gene Symbols: ANKS1B
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 261-510 of human ANKS1B (NP_858056.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG