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Invitrogen™ Ankyrin B Polyclonal Antibody
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Catalog No. PIPA583300
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PIPA583300 100 μL
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Catalog No. PIPA583300 Supplier Invitrogen™ Supplier No. PA583300
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DGVPKTEGDS SATALFPQTH KEQVQQDFSG KMQDLPEESS LEYQQEYFVT TPGTETSETQ KAMIVPSSPS KTPEEVSTPA EEEKLYLQTP TSSERGGSPI IQEPEEPSEH REESSPRKTS LVIVESADNQ PETCERLDED AAFE Highest antigen sequence indentity to the following orthologs: Rat - 64%, Mouse - 65%.

This gene encodes a member of the ankyrin family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton. Ankyrins play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. The protein encoded by this gene is required for targeting and stability of Na/Ca exchanger 1 in cardiomyocytes. Mutations in this gene cause long QT syndrome 4. Multiple transcript variants encoding different isoforms have been described.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Ankyrin B
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ANK2
Gene Accession No. Q01484
Gene Alias AI835472; Ank2; ANK-2; Ank3; AnkB; ankyrin 2, brain; ankyrin 2, neuronal; ankyrin 3, epithelial; ankyrin B; ankyrin, brain; ankyrin-2; ankyrin-2, nonerythrocytic; ankyrin-B; AW491075; Brain ankyrin; brank-2; LQT4; Non-erythroid ankyrin
Gene Symbols ANK2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ANK2. Recombinant protein control fragment (Product #RP-102424).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 287
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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