Ankyrin B Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-7631	100 μL

Catalog No. 50-198-7631 Supplier Bioss Supplier No. BS6967R

Description

Rabbit Polyclonal Antibody

This gene encodes a member of the ankyrin family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton. Ankyrins play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Most ankyrins are typically composed of three structural domains: an amino-terminal domain containing multiple ankyrin repeats; a central region with a highly conserved spectrin binding domain; and a carboxy-terminal regulatory domain which is the least conserved and subject to variation. The protein encoded by this gene is required for targeting and stability of Na/Ca exchanger 1 in cardiomyocytes. Mutations in this gene cause long QT syndrome 4. Multiple transcript variants encoding different isoforms have been described.

Specifications

• Antigen: Ankyrin B
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin)
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: ANK2
• Gene Accession No.: Q01484
• Gene Alias: AI835472; Ank2; ANK-2; Ank3; ANKB; ankyrin 2, brain; ankyrin 2, neuronal; ankyrin 3, epithelial; ankyrin B; ankyrin, brain; Ankyrin-2; ankyrin-2, nonerythrocytic; Ankyrin-B; AW491075; Brain ankyrin; brank-2; LQT4; Non-erythroid ankyrin
• Gene Symbols: ANK2
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human Ankyrin B.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 287
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG