Invitrogen™ Ankyrin G Monoclonal Antibody (2A8)

Catalog No.	Quantity
PIMA547397	100 μL
PIMA547299	500 μL

Catalog No. PIMA547397 Supplier Invitrogen™ Supplier No. MA547397

Description

Mouse Monoclonal Antibody

Ankyrin G Monoclonal Antibody for ICC/IF, IHC (PFA), Western Blot

Ankyrin-G is found in several tissues including brain where, due to tissue-specific RNA processing, it is expressed as two different isoforms, localized to axon initial segments and nodes of Ranvier. Ankyrin-G is also found at sites of epithelial cell-cell contact and in the intracellular membranes of some cells. Ankyrin-G isoforms contain a unique stretch of sequence highly enriched in serine and threonine residues immediately following a globular head domain. Ankyrin-G is thought to participate in the maintenance and targeting of ion channels and cell adhesion molecules to the nodes of Ranvier and to axon initial segments.

Specifications

• Antigen: Ankyrin G
• Applications: Immunohistochemistry (PFA fixed), Western Blot, Immunocytochemistry
• Classification: Monoclonal
• Clone: 2A8
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 5mM sodium azide
• Gene: ANK3
• Gene Accession No.: O70511, Q12955
• Gene Alias: 2900054D09Rik; AI314020; ANK3; ANK-3; AnkG; ankyrin 3; ankyrin 3 (G); ankyrin 3, epithelial; ankyrin 3, node of Ranvier (ankyrin G); ankyrin G; ankyrin-3; Ankyrin-G; brain-specific ankyrin-G; LOW QUALITY PROTEIN: ankyrin-3; MRT37
• Gene Symbols: ANK3
• Host Species: Mouse
• Immunogen: The C-terminal 398 amino acids of human ankyrin 3 expressed in and purified from E. coli.
• Purification Method: Protein A/G
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 288, 361833
• Target Species: Human, Rat
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1