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  5. Tocris Bioscience™ Anle138b

Tocris Bioscience™ Anle138b
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Catalog No. 686125
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Quantity:
5 mg
25 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Oligomeric aggregation inhibitor

Anle138b is a oligomeric aggregation inhibitor that inhibits formation of pathological prion protein (PrPSc) and α-synuclein aggregates in vitro. Anle138b prevents accumulation of PrPSc in brain and spleen, and prolongs survival of prion-infected mice. Anle138b exhibits neuroprotective effects in a Parkinson's disease mouse model and improves motor performance in an α-synucleinopathy model. Orally bioavailable and brain penetrant.

Specifications

Quantity 25 mg
Molecular Formula C16H11BrN2O2
Formula Weight 343.18
Product Type Inhibitor
Purity 98%
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