Invitrogen™ Annexin A1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA522266

Catalog No. PIPA522266

Description

Recommended positive controls: H1299, NIH-3T3, HeLa. Predicted reactivity: Mouse (86%), Rat (89%), Dog (92%), Cat (93%), Pig (87%), Rabbit (92%), Chimpanzee (99%), Bovine (89%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Annexin I belongs to a family of Ca (2+) -dependent phospholipid binding proteins that are preferentially located on the cytosolic face of the plasma membrane. Annexin I has a molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.

Specifications

• Antigen: Annexin A1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ANXA1
• Gene Alias: ANAX1; Annexin 1 (p35) (Lipocortin 1); annexin A1; Annexin I; annexin I (lipocortin I); annexin-1; ANX1; Anx-1; Anxa1; Anx-A1; C430014K04Rik; Calpactin II; calpactin-2; Chromobindin-9; lipocortin 1; lipocortin I; LPC1; Lpc-1; p35; Phospholipase A2 inhibitory protein; RP11-71A24.1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16952, 301
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P04083, P10107
• Gene Symbols: ANXA1
• Immunogen: Recombinant protein encompassing a sequence within the center region of human Annexin A1. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov