Invitrogen™ Annexin A2 Monoclonal Antibody (M009)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA547645

Catalog No. PIMA547645

Description

Clone M009 detects a 36 kDa* protein corresponding to the molecular mass of Annexin A2 on SDS-PAGE immunoblots of human A431, MDA-MB-231, MeWo, HUVEC, and PC3 cells. The antibody also works for ELISA, immunocytochemical labeling, and immunoprecipitation applications. In addition, mass spectrometry analysis of immunoprecipitates using AM0091 in human A431 cell lysates confirms that this antibody only detects Annexin A2 protein.

This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: Annexin A2
• Classification: Monoclonal
• Concentration: 0.2 mg/mL
• Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
• Gene Accession No.: P07355
• Gene Symbols: ANXA2
• Immunogen: Clone M009 was generated from a proprietary antigen related to human Annexin A2 in MDA-MB-231 breast cancer cell line.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: M009
• Conjugate: Unconjugated
• Gene: ANXA2
• Gene Alias: 33-kDa calcimedin; 33-kDa lymphocyte Ca>2+>- binding protein; 33kDa lymphocyte Ca>2+>- binding protein; 36-kDa calelectrin; annexin 2; annexin A2; annexin A2 isoform 2; annexin II; Annexin-2; ANX2; ANX2L4; ANXA2; AW215814; CAL1H; calpactin I heavy chain; calpactin I heavy chain (p36); calpactin I heavy polypeptide; calpactin-1 heavy chain; chromobindin 8; chromobindin-8; epididymis secretory protein Li 270; HEL-S-270; LIP2; lipocortin II; LPC2; LPC2D; p36; PAP-IV; Placental anticoagulant protein IV; protein I
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 302
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid