Invitrogen™ Annexin A2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588522

Catalog No. PIPA588522

Description

Immunogen sequence: MSTVHEILCK LSLEGDHSTP PSAYGSVKAY TNFDAERDAL NIETAIKTKG VDEVTIVNIL TNRSNAQRQD IAFAYQRRTK KELASALKSA LSGHLETVIL GLLKTPAQYD ASELKASMKG LGTDEDSLIE IICSRTNQEL QEINRVYKEM YKTDLEKDII SDTSGDFRKL MVALAKGRRA EDGSVIDYEL IDQDARDLYD AGVKRKGTDV PKWISIMTER SVPHLQKVFD RYKSYSPYDM LESIRKEVKG DLENAFLNLV QCIQNKPLYF ADRLYDSMKG KGTRDKVLIR IMVSRSEVDM LKIRSEFKRK YGKSLYYYIQ QDTKGDYQKA LLYLCGGDD; Positive Samples: SH-SY5Y, HepG2, Mouse lung; Cellular Location: Melanosome, basement membrane, extracellular matrix, extracellular space.

This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: Annexin A2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ANXA2
• Gene Alias: 33-kDa calcimedin; 33-kDa lymphocyte Ca>2+>- binding protein; 33kDa lymphocyte Ca>2+>- binding protein; 36-kDa calelectrin; annexin 2; annexin A2; annexin A2 isoform 2; annexin II; Annexin-2; ANX2; ANX2L4; ANXA2; AW215814; CAL1H; calpactin I heavy chain; calpactin I heavy chain (p36); calpactin I heavy polypeptide; calpactin-1 heavy chain; chromobindin 8; chromobindin-8; epididymis secretory protein Li 270; HEL-S-270; LIP2; lipocortin II; LPC2; LPC2D; p36; PAP-IV; Placental anticoagulant protein IV; protein I
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12306, 302, 56611
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.15 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P07355, P07356, Q07936
• Gene Symbols: ANXA2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-339 of human Annexin A2 (NP_0040301).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG