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Invitrogen™ Annexin A6 Polyclonal Antibody
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Catalog No. PIPA527462
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100 μL
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PIPA527462 100 μL
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Catalog No. PIPA527462 Supplier Invitrogen™ Supplier No. PA527462
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: H1299, NIH-3T3. Predicted reactivity: Mouse (95%), Rat (95%), Chicken (80%), Bovine (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Exon 21 of annexin VI is alternatively spliced, giving rise to two isoforms that differ by a 6-amino acid insertion at the start of the seventh repeat. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Annexin A6
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.179 mg/mL
Conjugate Unconjugated
Formulation PBS with 10% glycerol and 0.01% thimerosal; pH 7
Gene ANXA6
Gene Accession No. P08133, P14824
Gene Alias 67 kDa calelectrin; Annexin A6; annexin VI; annexin VI (p68); annexin VI, p68; annexin-6; Anx6; ANXA6; AnxVI; AW107198; Cabm; calcium-binding protein 65/67; calcium-binding protein CATA 65/67; calcium-binding protein p68; calelectrin; calphobindin II; calphobindin-II; Camb; CBP 65/67; CBP68; chromobindin-20; CPB-II; lipocortin VI; p68; p70; Protein III; testis secretory sperm-binding protein Li 198a
Gene Symbols ANXA6
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the C-terminus region of human Annexin VI. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11749, 309
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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