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Invitrogen™ ANO3 Polyclonal Antibody
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Catalog No. PIPA569654
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100 μL
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Catalog No. Quantity
PIPA569654 100 μL
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Catalog No. PIPA569654 Supplier Invitrogen™ Supplier No. PA569654
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Description

Rabbit Polyclonal Antibody

This target displays homology in the following species: Cow: 93%; Dog: 93%; Guinea Pig: 86%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 77%; Rat: 93%.

The protein encoded by this gene belongs to the TMEM16 family of predicted membrane proteins, that are also known as anoctamins. While little is known about the function of this gene, mutations in this gene have been associated with some cases of autosomal dominant craniocervical dystonia. Cells from individuals with a mutation in this gene exhibited abnormalities in endoplasmic reticulum-dependent calcium signaling. Studies in rat show that the rat ortholog of this protein interacts with, and modulates the activity of a sodium-activated potassium channel. Deletion of this gene caused increased pain sensitivity in the rat model system. Alternative splicing results in multiple transcript variants encoding different isoforms.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ANO3
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene ANO3
Gene Accession No. Q9BYT9
Gene Alias AI838058; ANO3; anoctamin 3; anoctamin-3; anoctamin-3; LOW QUALITY PROTEIN: anoctamin-3; B230324K02Rik; C11orf25; DYT23; DYT24; GENX-3947; Tmem16c; transmembrane protein 16C; transmembrane protein 16C (eight membrane-spanning domains)
Gene Symbols ANO3
Host Species Rabbit
Immunogen synthetic peptide directed towards the middle region of human ANO3.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 63982
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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