MilliporeSigma™ anti-20S Proteasome Core Subunits, Polyclonal

Catalog No.	Quantity	Conjugate
ST1053100UL	100 μL	Unconjugated

Catalog No. ST1053100UL Supplier MilliporeSigma™ Supplier No. ST1053100UL

Description

Rabbit Polyclonal Antibody

Specifically detects 20S Proteasome Core Subunits Clone: in Human, Mouse, Yeast samples, and it is validated for Immunohistochemistry (Paraffin), Immunoprecipitation

Proteasomes are large multi-subunit complexes, that are localized in the nucleus and cytosol, and selectively degrade intracellular proteins. They play a major role in the degradation of many proteins involved in cellular processes such as cell cycling, apoptosis, and proliferation. The human proteasome contains two copies of each of seven differentα-type andβ-type subunits assembled to form a stack of four seven-membered rings. Theα-subunits comprise the outer rings while theβ-subunits comprise the inner rings. Theβ-subunits are believed to be responsible for the proteolytic activity of the 20S proteasome.

Specifications

• Antigen: 20S Proteasome Core Subunits
• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation
• Classification: Polyclonal
• Conjugate: Unconjugated
• Formulation: Serum diluted in PBS.
• Host Species: Rabbit
• Immunogen: human erythrocyte proteasomes
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Recognizes the ∽25 to 30kDa 20S proteasome core subunits (α5,α7,β1,β5i, andβ7) in human erythrocytes, HeLa cells and 3T3 cells.
• Target Species: Human, Mouse, Yeast
• Content And Storage: −20°C
• Form: Serum
• Isotype: IgG

For Research Use Only