MilliporeSigma™ anti-A20 Clone: 59A426,

Mouse Monoclonal Antibody

Supplier:  MilliporeSigma™ AM63100UG

Catalog No. AM63100UG

Description

Specifically detects A20 Clone: 59A426 in Human samples, and it is validated for Immunoprecipitation

NF-κB (nuclear factor κB) regulates the expression of a large number of genes that play critical roles in apoptosis, viral replication, tumorigenesis, various autoimmune diseases and inflammation. The zinc finger protein A20 is a tumor necrosis factor and interleukin 1 (IL-1)-inducible protein that negatively regulates NF-κB gene expression by interferring with a novel TNF-induced and RIP- or TRAF2-mediated pathway that is different from the NIK-IκB kinase pathway. A20, an 70kDa protein, is expressed at low levels in most organs, the highest expression levels being in lymphoid tissues.

Specifications

• Antigen: A20
• Classification: Monoclonal
• Conjugate: Unconjugated
• Host Species: Mouse
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Form: Purified

• Applications: Immunoprecipitation
• Clone: 59A426
• Formulation: In PBS, 0.2% gelatin.
• Immunogen: full-length recombinant human A20 protein
• Regulatory Status: RUO
• Test Specificity: Recognizes the ∽70kDa A20 protein in Daudi cells.
• Content And Storage: −20°C
• Isotype: IgG1

For Research Use Only