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MilliporeSigma™ anti-A20 Clone: 59A426,

Catalog No. AM63100UG Shop All MilliporeSigma Products
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Quantity:
100 μg
Conjugate:
Unconjugated
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Catalog No. Quantity Conjugate
AM63100UG 100 μg Unconjugated
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Catalog No. AM63100UG Supplier MilliporeSigma™ Supplier No. AM63100UG
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Description

Mouse Monoclonal Antibody

Specifically detects A20 Clone: 59A426 in Human samples, and it is validated for Immunoprecipitation

NF-κB (nuclear factor κB) regulates the expression of a large number of genes that play critical roles in apoptosis, viral replication, tumorigenesis, various autoimmune diseases and inflammation. The zinc finger protein A20 is a tumor necrosis factor and interleukin 1 (IL-1)-inducible protein that negatively regulates NF-κB gene expression by interferring with a novel TNF-induced and RIP- or TRAF2-mediated pathway that is different from the NIK-IκB kinase pathway. A20, an 70kDa protein, is expressed at low levels in most organs, the highest expression levels being in lymphoid tissues.
TRUSTED_SUSTAINABILITY

Specifications

Antigen A20
Applications Immunoprecipitation
Classification Monoclonal
Clone 59A426
Conjugate Unconjugated
Formulation In PBS, 0.2% gelatin.
Host Species Mouse
Immunogen full-length recombinant human A20 protein
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Test Specificity Recognizes the ∽70kDa A20 protein in Daudi cells.
Target Species Human
Content And Storage −20°C
Form Purified
Isotype IgG1
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For Research Use Only

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