Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

ABCA1 Rabbit anti-Hamster, Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA132129

Catalog No. PA132129


Add to cart

Description

Description

PA1-32129 detects ABCA1 from rat, hamster, mouse, and human samples. PA1-32129 has been successfully used in immunocytochemistry, immunofluorescence, Western blot, immunohistochemistry (paraffin tissue), and immunoprecipitation applications. The PA1-32129 immunogen is a synthetic peptide: corresponding to amino acids 1100-1300 of Human ABCA 1. Immunogen sequence information is commercially sensitive and details are not available. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Mutations in the ABCA1 gene (ATP-binding cassette transporter 1) have been reported in Tangier disease (TD). TD is an autosomal recessive disorder characterized by an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and deviations in cellular lipid trafficking. ABCA1 mediates the apo-A1 associated export of cholesterol and phospholipids from the cell. It is expressed on the plasma membrane and the Golgi complex, and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI.
Specifications

Specifications

ABCA1
Polyclonal
Unconjugated
ABCA1
Liquid
ABCA1
synthetic peptide corresponding to amino acids 1100-1300 of Human ABCA 1.
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Hamster, Human, Mouse, Rat
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
1 mg/mL
PBS with 0.05% sodium azide; pH 7-8
O95477, P41233
ABC 1 antibody, ABC Transporter 1 antibody, ABC1 antibody, ATP-binding Cassette 1 antibody, ATP-binding Cassette Transporter 1 antibody, CERP antibody
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
100761226, 11303, 19, 313210
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit