MRP2 Mouse anti-Human, Clone: M2III-5, Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA135678
For immunohistochemistry (paraffin) applications, it is recommended to pretreat antibody with 0.01 M citric acid, pH 6.0, in distilled water at 100°C 3 times for 5 minutes.M2III-5 reacts with an internal epitope of MRP2, a 190-200 kD transmembrane protein earlier known as the canalicular multi-organic anion transporter cMOAT, absent in patients with the Dubin-Johnson syndrome, an autosomal recessive liver disorder characterized by chronic conjugated hyperbilirubinemia. MRP2 is a member of the MRP family of multidrug resistance related proteins, and MRP2 overexpression has been observed in a subset of cisplatin resistant cell lines.
|fusion protein of bacterial MBP and rat Mrp2, containing the 202-amino acid COOH terminal end|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot|
|tissue culture supernatant with 0.7% BSA and 0.1% sodium azide|
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