ABCD1, Mouse, Clone: 4B5, Abnova™

Catalog No.	Quantity
89-016-107	100 μg

Catalog No. 89-016-107 Supplier Abnova Corporation Supplier No. H00000215M01

Description

Mouse monoclonal antibody raised against a partial recombinant ABCD1.

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system. [provided by RefSeq

Sequence: MPVLSRPRPWRGNTLKRTAVLLALAAYGAHKVYPLVRQCLAPARGLQAPAGEPTQEASGVAAAKAGMNRVFLQRLLWLLRLLFPRVLCRETGLLALHSAA

Specifications

• Antigen: ABCD1
• Applications: ELISA
• Classification: Monoclonal
• Clone: 4B5
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against a partial recombinant ABCD1.
• Formulation: PBS with no preservative; pH 7.4
• Gene: ABCD1
• Gene Accession No.: BC015541
• Gene Alias: ABC42/ALD/ALDP/AMN
• Gene Symbols: ABCD1
• Host Species: Mouse
• Immunogen: ABCD1 (AAH15541, 1 a.a. ∼ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Purification Method: Affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 215
• Target Species: Human
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2a κ