Invitrogen™ H2BK15ac Recombinant Rabbit Monoclonal Antibody (7H17L5)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ 701799

Catalog No. PI701799

Description

Since it is highly conserved across species, the antibody may react with many other species. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The nucleosomes wrap further and compact DNA into chromotin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones play a central role in transciption regulation, DNA repair, DNA replication, and chromosomal stability. H2B has a broad antibacterial activity.

Specifications

• Antigen: H2BK15ac
• Classification: Recombinant Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.2
• Gene Accession No.: A0A2R8Y619, O60814, P06899, P0C1H6, P23527, P33778, P57053, P58876, P62807, Q16778, Q5QNW6, Q7Z2G1, Q8N257, Q93079, Q96A08, Q99877, Q99879, Q99880
• Gene Symbols: H2B, H2bc1, H2BC10, H2BC11, H2BC12, H2BC13, H2BC14, H2BC15, H2BC17, H2bc18, H2BC21, H2BC3, H2BC4, H2BC5, H2BC8, H2BC9, H2BE1, H2BU1, H2BW1, H2BW2, LOC102724334
• Immunogen: Acetylated peptide (Lys15) corresponding to Human H2 (aa 11-18).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Peptide Array, Western Blot, Immunocytochemistry
• Clone: 7H17L5
• Conjugate: Unconjugated
• Gene: H2BW2
• Gene Alias: 2610022J01Rik; Acetyl-Histone H2; Acetyl-Histone H2B K15; Acetyl-Histone H2B Lys15; AV127319; bA317E16.3; dJ160A22.3; dJ193B12.2; dJ221C16.3; dJ221C16.6; dJ221C16.8; dJ97D16.4; GL105; H2B; H2B 291A; H2B 291B; H2b 613; H2B GL105; H2B histone family member M; H2B histone family member W testis-specific; H2B histone family member W, testis specific; H2B histone family, member A; H2B histone family, member B; H2B histone family, member C; H2B histone family, member D; H2B histone family, member E; H2B histone family, member F; H2B histone family, member J; H2B histone family, member K; H2B histone family, member L; H2B histone family, member M; H2B histone family, member N; H2B histone family, member Q; H2B histone family, member R; H2B histone family, member S; H2B histone family, member T; H2B histone family, member U, (testis-specific); H2B histone family, member W, testis-specific; H2B K; H2B type 12; H2B.1; H2B.1A; H2B.1B; H2B.2; H2B/a; H2B/b; H2B/c; H2B/d; H2B/e; H2B/f; H2B/g; H2B/h; H2B/I; H2B/j; H2B/k; H2B/l; H2B/n; H2B/o; H2B/q; H2B/r; H2B/s; H2B/t; h2B-143; H2b-221; H2b-291b; H2b-613; H2Bb; H2BC10; H2BC4; H2BC6; H2BC7; H2BC8; H2b-f; H2BFA; H2BFAiii; H2BFB; H2BFC; H2BFD; H2BFE; H2BFF; H2BFG; H2BFH; H2BFJ; H2BFK; H2BFL; H2BFM; H2BFN; H2BFO; H2BFQ; H2BFR; H2bfs; H2BFT; H2BFU; H2BFWT; H2BGL105; H2BJ; H2b-j; H2BK; H2BK12ac; H2BK15ac; H2BK5ac; H2b-l; H2BLys15ac; H2b-n; H2BQ; H2BS14; H2BS14p; HIRA-interacting protein 1; HIRA-interacting protein 2; HIRIP1; HIRIP2; HIST1H2BA; HIST1H2BB; Hist1h2bc; HIST1H2BD; HIST1H2BE; Hist1h2bf; Hist1h2bg; HIST1H2BH; HIST1H2BI; HIST1H2BJ; Hist1h2bk; HIST1H2BL; Hist1h2bm; Hist1h2bn; HIST1H2BO; HIST1H3I; HIST2H2BC; HIST2H2BD; Hist2h2be; HIST2H2BF; HIST3H2BB; histone 1, H2ba; histone 1, H2bb; histone 1, H2bc; histone 1, H2bd; histone 1, H2bg; histone 1, H2bh; histone 1, H2bi; histone 1, H2bj; histone 1, H2bk; histone 1, H2bl; histone 1, H2bm; histone 1, H2bn; histone 1, H2bo; histone 2, H2be; Histone 2B; histone 3, H2bb; histone cluster 1, H2ba; histone cluster 1, H2bb; histone cluster 1, H2bc; histone cluster 1, H2bd; histone cluster 1, H2bg; histone cluster 1, H2bh; histone cluster 1, H2bi; histone cluster 1, H2bj; histone cluster 1, H2bk; histone cluster 1, H2bl; histone cluster 1, H2bm; histone cluster 1, H2bn; histone cluster 1, H2bo; histone cluster 2, H2bc (pseudogene); histone cluster 2, H2bd (pseudogene); histone cluster 2, H2be; histone cluster 2, H2bf; histone cluster 3, H2bb; histone family member; histone H2B; histone H2B type 1-A; Histone H2B type 1-B; histone H2B type 1-C/E/F/G/I; Histone H2B type 1-C/E/G; histone H2B type 1-D; Histone H2B type 1-F/J/L; histone H2B type 1-H; Histone H2B type 1-J; histone H2B type 1-K; Histone H2B type 1-L; histone H2B type 1-M; Histone H2B type 1-N; histone H2B type 1-O; Histone H2B type 2-E; histone H2B type 2-F; Histone H2B type 3-B; histone H2B type F-M; Histone H2B type F-S; histone H2B type F-S-like; histone H2B type W-T; Histone H2B, testis; Histone H2B.1; histone H2B.1 A; Histone H2B.1 B; histone H2B.2; Histone H2B.a; histone H2B.b; Histone H2B.c; histone H2B.d; Histone H2B.e; histone H2B.f; Histone H2B.g; Histone H2B.h; Histone H2B.I; Histone H2B.j; histone H2B.k; Histone H2B.l; histone H2B.n; Histone H2B.q; histone H2B.r; Histone H2B.s; histone H2B-GL105; LOC102724334; MGC125414; MGC125415; MGC125416; MGC9388; R74621; RGD1562346; RP1-193B12.10; STBP; T25626; testis-specific histone 2b; testis-specific histone H2B; Th2b; TSH2B; TSH2B.1
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 102724334, 114483833, 128312, 158983, 255626, 286436, 3017, 3018, 440689, 8339, 8340, 8341, 8342, 8345, 8346, 8347, 8348, 8349, 85236, 8970
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid