MilliporeSigma™ anti-acetyl-Histone H4 (Lys16), Alexa Fluor 488, Polyclonal

Rabbit Polyclonal Antibody

Supplier:  MilliporeSigma™ 07329AF488

Catalog No. 07-329-AF488

Description

Specifically detects acetyl-Histone H4 (Lys16) Clone: in Human, Mouse samples, and it is validated for Immunohistochemistry

Histone H4 (UniProt P02309) is encoded by the HHF1 (ORF YBR0122; Gene ID 852294) and HHF2 (ORF N2752; Gene ID 855701) genes in yeast species. Histone H4 is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N terminal tail, H4 is involved with the structure of the nucleosomes of the 'beads on a string' structure. Acetylation of histone H4 occurs at several different lysine positions in the histone tail and is performed by a family of enzymes known as Histone Acetyl Transferases (HATs).

Specifications

• Antigen: acetyl-Histone H4 (Lys16)
• Classification: Polyclonal
• Formulation: Purified rabbit antibody conjugate in PBS with 15mg/mL BSA and 0.1 % sodium azide.
• Gene Symbols: HHF1, YBR009C, YBR0122, HHF2, YNL030W, N2752
• Immunogen: Ovalbumin-conjugated, synthetic peptide (…GAAcKRH …) in which AcK corresponds to residue 16 of yeast histone H4.
• Quantity: 100 μL
• Research Discipline: Epigenetics, Nuclear Function
• Gene ID (Entrez): NP_009563.1
• Target Species: Human, Mouse
• Form: Purified

• Applications: Immunohistochemistry
• Conjugate: Alexa Fluor 488
• Gene Accession No.: P02309
• Host Species: Rabbit
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: H4K16ac specificity of the unconjugated antibody has been confirmed using the Absurance™ Histone H3 Antibody Specificity Array and the Absurance™ Histone H2A, H2B, H4 Antibody Specificity Array.
• Content And Storage: 2°C to 8°C for one year

For Research Use Only