ACMSD Mouse anti-Human, Clone: 3A9, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA523009
Peptide Sequence: SHGFSMRPDL CAQDNPMNPK KYLGSFYTDA LVHDPLSLKL LTDVIGKDKV ILGTDYPFPL GELEPGKLIE SMEEFDEETK NKLKAGNALA FLGLERKQFEThe neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 126.96.36.199) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.
|PBS with no preservative; pH 7.4|
|2-amino-3-carboxymuconate-6-semialdehyde decarboxylase, picolinate carboxylase|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Western Blot|
|ACMSD (NP_612199, 179 a.a. ∽ 278 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.|
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