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ACMSD Mouse anti-Human, Clone: 3A9, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA523009

Catalog No. PIMA523009


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Description

Description

Peptide Sequence: SHGFSMRPDL CAQDNPMNPK KYLGSFYTDA LVHDPLSLKL LTDVIGKDKV ILGTDYPFPL GELEPGKLIE SMEEFDEETK NKLKAGNALA FLGLERKQFE

The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.
Specifications

Specifications

ACMSD
Monoclonal
0.2-1.0 mg/mL
PBS with no preservative; pH 7.4
Q8TDX5
2-amino-3-carboxymuconate-6-semialdehyde decarboxylase, picolinate carboxylase
Mouse
IgG2b, kappa
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
130013
ELISA, Western Blot
3A9
Unconjugated
ACMSD
Liquid
ACMSD
ACMSD (NP_612199, 179 a.a. ∽ 278 a.a) partial recombit protein with GST tag. MW of the GST tag alone is 26 KDa.
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Documents
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