Invitrogen™ ACMSD Monoclonal Antibody (3A9)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA523009

Catalog No. PIMA523009

Description

Peptide Sequence: SHGFSMRPDL CAQDNPMNPK KYLGSFYTDA LVHDPLSLKL LTDVIGKDKV ILGTDYPFPL GELEPGKLIE SMEEFDEETK NKLKAGNALA FLGLERKQFE.

The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.[supplied by OMIM, Oct 2004].

Specifications

• Antigen: ACMSD
• Classification: Monoclonal
• Concentration: 0.2-1.0 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: Q8TDX5
• Gene Symbols: ACMSD
• Immunogen: ACMSD (NP_612199, 179 a.a. ~ 278 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b κ

• Applications: ELISA, Western Blot
• Clone: 3A9
• Conjugate: Unconjugated
• Gene: ACMSD
• Gene Alias: 2-amino-3-carboxylmuconate-6-semialdehyde decarboxylase; 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Acmsd; amino carboxymuconate semialdehyde decarboxylase; aminocarboxymuconate semialdehyde decarboxylase; Picolinate carboxylase; zgc:162888
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 130013
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid