MilliporeSigma™ anti-Actin, Clone: C4, ™ (Chemicon™)

Supplier:  MilliporeSigma™ MAB1501/DEL

Catalog No. 50-174-848

Description

Actin is an abundant cytoskeletal protein found in all cells (True, 1990). The protein's 42 kD peptide chain assumes two physical forms: globular actin, which may serve as a cytoplasmic storage pool, and fibrous actin, which, in conjunction with myosin, generates muscle contraction (True, 1990). In non-muscle cells, actin appears to be involved in a variety of functions, such as cell motility, exocytosis, and phagocytosis (True, 1990). Distribution of the six known isoforms of actin - four muscle actins (α-skeletal, α-vascular smooth, α-cardiac, and γ-enteric smooth) and two cytoplasmic actins (α and γ) is tissue specific (Otey, 1986; Lessard, 1988).

Lessard, 1988.

ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blotting

Specifications

• Antigen: Actin
• Conjugate: Unconjugated
• Immunogen: Purified chicken gizzard actin
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Isotype: IgG1 κ

• Classification: Monoclonal
• Host Species: Mouse
• Quantity: 100 μL
• Research Discipline: Cell Structure
• Form: Ascites