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MilliporeSigma™ anti-Actin Clone: JLA20,

Catalog No. CP011EA Shop All MilliporeSigma Products
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Unconjugated
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CP011EA 1 Kit Unconjugated
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Description

Mouse Monoclonal Antibody

Specifically detects Actin Clone: JLA20 in samples, and it is validated for Immunofluorescence

Cytoskeletal proteins are found in highly organized arrays within the cytoplasm of higher eukaryotic cells. These proteins are intimately involved in functions such as cell and intracellular organelle movement, maintenance of cell shape and endocytosis. The cytoskeleton of most eukaryotic cells is comprised of at least three fibrous systems each with accessory proteins: the microfilaments, composed of actin; the microfibrils, composed of tubulin; and the intermediate filaments composed of vimentin. Monoclonal antibodies have been used to study the components of the cytoskeleton and their intracellular location, changes in the expression of these elements during differentiation, and the function of the cytoskeleton in living cells by microinjection of the antibodies.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Actin
Applications Immunofluorescence
Classification Monoclonal
Clone JLA20
Conjugate Unconjugated
Formulation 100μL ascites diluted in 5mM sodium phosphate buffer, pH 7.5 and 5μg anti-mouse IgM, HRP conjugate supplied at 100μg/ml in 0.05M sodium phosphate, 50% glycerol.
Host Species Mouse
Immunogen chicken cytoskeletal proteins
Quantity 1 Kit
Regulatory Status RUO
Primary or Secondary Primary
Test Specificity Recognizes the ∽42kDa α-, β-, and γ isoforms of actin. Useful as a positive control antibody. Antibody Target Gene Symbol: ACTA1, ACTB1, ACTG1 Target Synonym: AA959943, ACTA, Acta-2, Acts, Actsk-1, ALPHA SKELETAL ACTIN, ALPHA1 ACTIN, ASMA, CFTD, CFTD1, CFTDM, Fetal isoform of skeletal alpha-actin, G-actin, MPFD, NEM1, NEM2, NEM3, SKA, SKELETAL ALPHA-ACTIN, SKELETAL MUSCLE ACTIN Entrez Gene Name: actin, alpha 1, skeletal muscle
Content And Storage −20°C
Form Ascites
Isotype IgM
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For Research Use Only

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